1940 The Realm of Spirit: Book Fourth of Realms of Being published. The Philosophy of George Santayana published in December.

1941 Santayana moves into a nursing home operated by the Blue Sisters of the Little Company of Mary, an order of Roman Catholic Irish nuns.

1944 Persons and Places published in December; becomes a bestseller.

1945 The Middle Span published. Santayana awarded the Nicholas Murray Butler Medal by Columbia University.

1946 The Idea of Christ in the Gospels; or, God in Man: A Critical Essay published.

1948 Dialogues in Limbo, With Three New Dialogues published.